W Taylor Kimberly Selected Research

Amyloid Precursor Protein Secretases (beta-Secretase)

5/2003	Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2.
1/2003	Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

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W Taylor Kimberly Research Topics

Disease

39	Stroke (Strokes) 04/2024 - 09/2012
22	Edema (Dropsy) 01/2022 - 09/2012
20	Ischemic Stroke 04/2024 - 01/2011
20	Brain Edema (Cerebral Edema) 03/2024 - 08/2013
14	Infarction (Infarctions) 11/2021 - 01/2011
7	Brain Injuries (Brain Injury) 10/2022 - 01/2012
6	Alzheimer Disease (Alzheimer's Disease) 06/2005 - 03/2002
5	Brain Ischemia (Cerebral Ischemia) 01/2020 - 09/2012
5	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2020 - 04/2015
4	Hypertension (High Blood Pressure) 04/2024 - 01/2022
3	Ischemia 03/2021 - 01/2014
3	Hydrocephalus (Hydrocephaly) 11/2019 - 04/2014
2	Cerebral Hemorrhage 12/2022 - 01/2021
2	Coma (Comas) 10/2022 - 01/2020
2	Heart Arrest (Cardiac Arrest) 10/2022 - 01/2018
2	Neoplasms (Cancer) 01/2022 - 09/2021
2	COVID-19 09/2021 - 10/2020
2	Hemorrhage 01/2020 - 01/2017
2	Infections 04/2019 - 01/2016
2	Embolic Stroke 01/2019 - 05/2013
1	Craniocerebral Trauma (Head Injury) 05/2024
1	Chronic Renal Insufficiency 04/2024
1	Intracranial Hypertension 03/2024
1	Neurogenic Inflammation 03/2024
1	Atherosclerosis 01/2023
1	Cerebral Small Vessel Diseases 01/2023
1	Lacunar Stroke 01/2023
1	Bronchiolitis Obliterans Syndrome 01/2022
1	Inflammation (Inflammations) 01/2022
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2021
1	Vascular System Injuries 12/2021
1	Hyperglycemia 01/2021
1	Critical Illness (Critically Ill) 09/2020
1	Brain Contusion 01/2020
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2020

Drug/Important Bio-Agent (IBA)

18	Glyburide (Glibenclamide)FDA LinkGeneric 01/2022 - 09/2012
17	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2012
5	Proteins (Proteins, Gene)FDA Link 05/2024 - 05/2003
5	Sulfonylurea ReceptorsIBA 01/2020 - 09/2012
5	Matrix Metalloproteinase 9 (Gelatinase B)IBA 12/2018 - 09/2012
3	GuanosineIBA 03/2024 - 01/2022
3	gluconic acid (gluconate)FDA LinkGeneric 01/2023 - 01/2021
3	Endothelin-1 (Endothelin 1)IBA 10/2022 - 09/2021
3	Tissue Plasminogen Activator (Alteplase)FDA Link 06/2017 - 09/2012
3	Hemoglobins (Hemoglobin)IBA 06/2015 - 01/2011
3	Amyloid beta-PeptidesIBA 06/2005 - 05/2003
2	Uric Acid (Urate)IBA 04/2024 - 01/2021
2	Betaine (C.B.B.)FDA Link 04/2024 - 01/2023
2	AcidsIBA 03/2024 - 10/2022
2	Carnitine (L-Carnitine)FDA LinkGeneric 01/2023 - 01/2023
2	Betulinic AcidIBA 10/2022 - 01/2019
2	AntioxidantsIBA 10/2022 - 01/2019
2	signal peptide receptorIBA 01/2022 - 09/2021
2	CytokinesIBA 12/2021 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 12/2014
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2020
2	Oxygen (Dioxygen)IBA 10/2020 - 01/2011
2	Peptide Hydrolases (Proteases)FDA Link 11/2003 - 03/2002
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 05/2003 - 01/2003
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 04/2024
1	BilirubinIBA 04/2024
1	indole-3-lactic acidIBA 04/2024
1	Leucine (L-Leucine)FDA Link 04/2024
1	Phosphatidylethanolamines (Cephalins)IBA 04/2024
1	Docosahexaenoic AcidsIBA 04/2024
1	LipidsIBA 04/2024
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 04/2024
1	Tachykinin Receptors (Tachykinin Receptor)IBA 03/2024
1	Substance PIBA 03/2024
1	CotinineIBA 03/2024
1	P-2 (P 2)IBA 03/2024
1	trimethyloxamine (trimethylamine N-oxide)IBA 01/2023
1	Choline (Choline Chloride)IBA 01/2023
1	AnticoagulantsIBA 12/2022
1	Peptide Receptors (Peptide Receptor)IBA 10/2022
1	Peptides (Polypeptides)IBA 10/2022
1	Drug CarriersIBA 10/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	HypoxanthineIBA 01/2022
1	PseudouridineIBA 01/2022
1	NucleosidesIBA 01/2022
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2021
1	LigandsIBA 09/2021
1	Galectin 3 (LGALS3)IBA 01/2021
1	dimethylarginineIBA 01/2021
1	Fatty Acid-Binding ProteinsIBA 01/2021

Therapy/Procedure

11	Therapeutics 03/2024 - 04/2014
6	Decompressive Craniectomy 12/2016 - 04/2014
5	Thrombectomy 01/2022 - 06/2017
4	Critical Care (Surgical Intensive Care) 09/2020 - 04/2014
3	Ventriculostomy 04/2019 - 04/2014
2	Intravenous Administration 10/2022 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2016
2	Embolectomy 10/2018 - 01/2018
2	Tracheostomy 08/2014 - 05/2014
1	Dietary Approaches To Stop Hypertension 01/2023
1	Plant-Based Diet 01/2023
1	Induced Hypothermia 10/2022
1	Cell Transplantation 01/2022